LAT antibody (pTyr161)
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- Target See all LAT Antibodies
- LAT (Linker For Activation of T Cells (LAT))
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Binding Specificity
- pTyr161
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LAT antibody is un-conjugated
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Application
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat,Cow
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr161
- Isotype
- IgG
- Top Product
- Discover our top product LAT Primary Antibody
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anti-Linker For Activation of T Cells (LAT) antibody
LAT Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibodyLAT Reactivity: Human WB, IP, FACS Host: Mouse Monoclonal LAT-01 unconjugated
anti-Linker For Activation of T Cells (LAT) (pTyr191) antibodyLAT Reactivity: Human WB, ELISA, IHC, IP, IF Host: Rabbit Monoclonal 2E4 unconjugated Recombinant Antibody
anti-Linker For Activation of T Cells (LAT) (AA 1-233) antibodyLAT Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 3B11-1D5 unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 30-237) antibodyLAT Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibodyLAT Reactivity: Human WB, IP, IHC (p) Host: Mouse Monoclonal LAT1111 unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 25-221) antibodyLAT Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 33-227) antibodyLAT Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (Tyr255) antibodyLAT Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (Tyr660) antibodyLAT Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- LAT (Linker For Activation of T Cells (LAT))
- Alternative Name
- LAT (LAT Products)
- Synonyms
- LAT antibody, lat antibody, LAT1 antibody, pp36 antibody, linker for activation of T-cells antibody, linker for activation of T cells antibody, LAT antibody, lat antibody, Lat antibody
- Background
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Synonyms: LAT1, pp36, Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, p36-38, LAT
Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
- Gene ID
- 27040
- UniProt
- O43561
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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