LDLR antibody

Catalog No. ABIN6943913

This anti-LDLR antibody is a Rabbit Monoclonal antibody detecting LDLR in WB, IHC, FACS, IHC (p) and IF (cc). Suitable for Human and Mouse.

Quick Overview for LDLR antibody (ABIN6943913)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LDLR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 1A7

Product Details anti-LDLR Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Synthetic peptide of C terminal Human LDL Receptor

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Alternative Name: LDL Receptor

Background:

Synonyms: Low-density lipoprotein receptor, LDL receptor

Background: Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

Gene ID: 3949

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism