LDLR antibody

Catalog No. ABIN6943913

The Rabbit Monoclonal anti-LDLR antibody (Clone 1A7) (ABIN6943913) specifically detects LDLR in WB, IHC, FACS, IHC (p) and IF (cc). The antibody is reactive with Human and Mouse samples.

Quick Overview for LDLR antibody (ABIN6943913)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LDLR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 1A7

Product Details anti-LDLR Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Synthetic peptide of C terminal Human LDL Receptor

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Alternative Name: LDL Receptor

Background:

Synonyms: Low-density lipoprotein receptor, LDL receptor

Background: Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

Gene ID: 3949

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism