Recombinant NRF1 antibody (AA 300-450)

Catalog No. ABIN6944318

The Rabbit Monoclonal anti-NRF1 antibody (ABIN6944318) specifically detects NRF1 in WB, FACS, IF, IHC (p), ICC and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for Recombinant NRF1 antibody (AA 300-450) (ABIN6944318)

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NRF1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NRF1 Antibody

Binding Specificity: AA 300-450

Purpose: NRF1 Recombinant Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human NRF1 aa 300-450

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:20-100), IHC-F(1:200-400), IF(1:50-200), Flow-Cyt(1:50-200), ICC/IF(1:50-100)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NRF1

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Alternative Name: NRF1

Background:

Synonyms: Nuclear respiratory factor 1, Alpha palindromic-binding protein, NRF-1, Alpha-pal, NRF1.

Background: Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.

Gene ID: 4899

UniProt: Q16656

Pathways: Regulation of Lipid Metabolism by PPARalpha