NudC Domain Containing 1 (NUDCD1) (AA 431-530) antibody (Biotin)

Details for Product No. ABIN6944331
Antigen
  • Cml66
  • NUDCD1
  • CML66
  • OVA66
  • 4921532K09Rik
  • AA407246
  • AW260430
  • AW556235
  • CML66-L
  • RGD1310624
  • im:6901299
  • im:6912119
  • wu:fc11c02
  • zgc:110705
  • cml66
  • NudC domain containing 1
  • NudC domain-containing protein 1
  • NudC domain containing 1 S homeolog
  • NUDCD1
  • nudcd1
  • CpipJ_CPIJ019282
  • nudc1
  • LOC777229
  • Nudcd1
  • nudcd1.S
Epitope
AA 431-530
9
8
8
7
7
3
2
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
34
14
14
4
4
4
3
3
2
2
1
1
Host
Rabbit
34
Clonality
Polyclonal
Conjugate
Biotin
5
4
2
2
2
2
Application
Western Blotting (WB)
34
15
2
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human NUDCD1
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name NUDCD1
Background

The NUDCD1 gene encodes the 583 amino acid CML66 protein which demonstrates expression in a variety of solid tumor cell lines and leukemias. Expression of CML66 in normal tissues is restricted to testis and heart. The CML66 antibody is found in sera of 18-38 % of patients with lung cancer, melanoma or prostate cancer. These findings indicate that CML66 may be immunogenic in a wide variety of malignancies and may be a target for antigen-specific immunotherapy. A short isoform of CML66, designated CML66-S, is a product of alternative splicing. CML66-S has the same C-terminus as full-lenghth CML66 (also designated CML66-L), but has a unique N-terminus. CML66-S shows predominant expression in testis, and is also expressed in very low levels in tumor cells, while CML66 is expressed in tumor cells and testis.


Synonyms: 4921532K09Rik, AA407246, AW260430, AW556235, Chronic myelogenous leukemia tumor antigen 66, CML66, CML66 L, FLJ14991, NudC domain containing 1, NudC domain-containing protein 1, NUDC1_HUMAN, nudcd1, OVA66, RGD1310624, Tumor antigen CML66.
Gene ID 84955
UniProt Q96RS6
Application Notes WB(1:300-1000)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Did you look for something else?