Recombinant Periostin antibody (C-Term)

Catalog No. ABIN6944485

The Rabbit Monoclonal anti-Periostin antibody is suitable to detect Periostin in samples from Human. It has been validated for WB, IHC (p), FACS, IHC (fro) and IF (p).

Quick Overview for Recombinant Periostin antibody (C-Term) (ABIN6944485)

Target: Periostin (POSTN)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Periostin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Periostin Antibody

Binding Specificity: C-Term

Purpose: Periostin Recombinant Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Human Perilipin-1 aa 400 to the C-terminus

Isotype: IgG

Application Details

Application Notes: WB(WB(1:500-2000)), FCM(FCM(1:20-50)), IHC-P(IHC-P(1:100-500)), IHC-F(IHC-F(1:100-500)), IF(IHC-P)(IF(IHC-P)(1:100-500))

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Periostin

Target: Periostin (POSTN)

Alternative Name: Periostin

Background:

Synonyms: Periostin, Osteoblast-specific factor 2, PN, OSF-2, POSTN, OSF2, PDLPOSTN.

Background: Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide-linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta and alpha(V)beta integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor _ 1(TGF _ 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.

Gene ID: 10631

UniProt: Q15063