This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. This gene appears to be a polymorphic pseudogene in humans, where some individuals contain a non-functional allele. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Synonyms: PC1 like 2 protein, PC1-like 2 protein, PK1L2_HUMAN, PKD1L 2, Pkd1l2, Polycystic kidney disease 1 like protein 2, Polycystic kidney disease 1-like protein 2, Polycystic kidney disease protein 1-like 2, Polycystin 1 like 2, Polycystin-1L2.