Plexin A1 antibody (AA 1-200)

Catalog No. ABIN6944618

The Rabbit Monoclonal anti-Plexin A1 antibody (Clone 2G1) (ABIN6944618) specifically detects Plexin A1 in WB, FACS and IF (cc). The antibody is reactive with Human samples.

Quick Overview for Plexin A1 antibody (AA 1-200) (ABIN6944618)

Target: Plexin A1 (PLXNA1)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Plexin A1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 2G1

Product Details anti-Plexin A1 Antibody

Binding Specificity: AA 1-200

Purpose: Plexin A1 (2G1) Monoclonal Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human Plexin A1 aa 1-200

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), FCM(1:20-100), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Plexin A1

Target: Plexin A1 (PLXNA1)

Alternative Name: PLXNA1

Background:

Synonyms: Plexin-A1, Semaphorin receptor NOV, PLXNA1, NOV, PLXN1

Background: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Gene ID: 5361

UniProt: Q9UIW2

Pathways: Smooth Muscle Cell Migration