Plexin A1 antibody

Catalog No. ABIN6944618

The Rabbit Monoclonal anti-Plexin A1 antibody (Clone 2G1) (ABIN6944618) specifically detects Plexin A1 in WB, FACS and IF (cc). The antibody is reactive with Human samples.

Quick Overview for Plexin A1 antibody (ABIN6944618)

Target: Plexin A1 (PLXNA1)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Plexin A1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 2G1

Product Details anti-Plexin A1 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human Plexin A1 aa 1-200

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Plexin A1

Target: Plexin A1 (PLXNA1)

Alternative Name: PLXNA1

Background:

Synonyms: Plexin-A1, Semaphorin receptor NOV, PLXNA1, NOV, PLXN1

Background: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Gene ID: 5361

UniProt: Q9UIW2

Pathways: Smooth Muscle Cell Migration