Plexin A1 (PLXNA1) antibody

Details for Product No. ABIN6944618
Antigen
  • PLXNA1
  • NOV
  • NOVP
  • PLEXIN-A1
  • PLXN1
  • 2600013D04Rik
  • PlexA1
  • Plxn1
  • mKIAA4053
  • plexin A1
  • plexin A1 L homeolog
  • plexin A1b
  • PLXNA1
  • plxna1.L
  • plxna1b
  • plxna1
  • Plxna1
Reactivity
Human
64
33
23
Host
Rabbit
58
6
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
7
4
4
4
4
4
4
4
4
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
22
21
13
7
6
4
4
3
2
2
1
Options
Immunogen Recombinant protein within human Plexin A1 aa 1-200
Clone 2G1
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name PLXNA1 (PLXNA1 Antibody Abstract)
Background

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Subcellular location: Cell membrane


Synonyms: Plexin-A1, Semaphorin receptor NOV, PLXNA1, NOV, PLXN1
Gene ID 5361
UniProt Q9UIW2
Pathways Smooth Muscle Cell Migration
Application Notes FCM(1:50-100), IF(ICC)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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