PMP22 antibody (Peripheral Myelin Protein 22)

Details for Product anti-PMP22 Antibody No. ABIN6944620
Antigen
  • CMT1A
  • CMT1E
  • DSS
  • GAS-3
  • HMSNIA
  • HNPP
  • Sp110
  • 22kDa
  • Gas-3
  • Tr
  • trembler
  • pmp22
  • wu:fa04d03
  • wu:fa08d03
  • MGC80653
  • PMP22
  • MGC69407
  • peripheral myelin protein 22
  • peripheral myelin protein 22a
  • peripheral myelin protein 22 S homeolog
  • PMP22
  • Pmp22
  • pmp22a
  • pmp22.S
  • pmp22
Reactivity
Human, Mouse (Murine), Rat (Rattus)
96
45
38
4
3
2
2
1
1
1
1
Host
Rabbit
88
16
Clonality (Clone)
Monoclonal ()
Conjugate
This PMP22 antibody is un-conjugated
7
4
4
4
4
4
4
4
4
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
52
34
22
22
15
8
7
6
5
2
2
2
1
1
Options
Immunogen Full length protein
Clone 1A11
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PMP22 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PMP22 (PMP22 Antibody Abstract)
Background

PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.


Synonyms: Peripheral myelin protein 22, Growth arrest-specific protein 3, PMP-22, GAS-3, PMP22, GAS3
Gene ID 5376
UniProt Q01453
Application Notes WB(1:500-1000), FCM(1:50-100), IHC-P(1:50-200), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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