PMP22 antibody

Catalog No. ABIN6944620

Product Details anti-PMP22 Antibody

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PMP22 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Full length protein

Clone: 1A11

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PMP22

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Alternative Name: PMP22 (PMP22 Products)

Synonyms: CMT1A antibody, CMT1E antibody, DSS antibody, GAS-3 antibody, HMSNIA antibody, HNPP antibody, Sp110 antibody, 22kDa antibody, Gas-3 antibody, Tr antibody, trembler antibody, pmp22 antibody, wu:fa04d03 antibody, wu:fa08d03 antibody, MGC80653 antibody, PMP22 antibody, MGC69407 antibody, id:ibd2630 antibody, wu:fb81f09 antibody, zgc:136919 antibody, peripheral myelin protein 22 antibody, peripheral myelin protein 22a antibody, peripheral myelin protein 22 S homeolog antibody, peripheral myelin protein 22b antibody, PMP22 antibody, Pmp22 antibody, pmp22a antibody, pmp22.S antibody, pmp22 antibody, pmp22b antibody

Background:

Synonyms: Peripheral myelin protein 22, Growth arrest-specific protein 3, PMP-22, GAS-3, PMP22, GAS3

Background: PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.

Gene ID: 5376

UniProt: Q01453