POR antibody (P450 (Cytochrome) Oxidoreductase)

Details for Product anti-POR Antibody No. ABIN6944641
Antigen
  • CPR
  • CYPOR
  • P450R
  • POR
  • CCR
  • CG11567
  • DMR
  • DmCPR
  • Dmel\\CG11567
  • NCPR
  • P450
  • cpr
  • zgc:110032
  • npr
  • xpor
  • 4933424M13Rik
  • PORCINO
  • T5J17.90
  • T5J17_90
  • TFC C
  • TUBULIN-FOLDING COFACTOR C
  • cytochrome p450 oxidoreductase
  • P450 (cytochrome) oxidoreductase
  • Cytochrome P450 reductase
  • P450 (cytochrome) oxidoreductase a
  • P450 (cytochrome) oxidoreductase L homeolog
  • NADPH--cytochrome P450 reductase
  • C-CAP/cofactor C-like domain-containing protein
  • POR
  • Por
  • Cpr
  • pora
  • por.L
  • LOC100406157
  • por
  • LOC100619047
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
98
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3
Clonality (Clone)
Monoclonal ()
Conjugate
This POR antibody is un-conjugated
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4
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Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Options
Immunogen Recombinant protein within human Cytochrome P450 Reductase aa 1-150
Clone 4F7
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others POR products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name POR (POR Antibody Abstract)
Background

Cytochrome P450 Oxidoreductase is an endoplasmic reticulum membrane oxidoreductase with a FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. It can also provide electron transfer to heme oxygenase and cytochrome B5.

Subcellular location: Endoplasmic Reticulum


Synonyms: NADPH cytochrome P450 reductase, CPR, P450R, POR, CYPOR, Cytochrome p450 Reductase
Gene ID 5447
UniProt P16435
Pathways Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
Application Notes WB(1:500-1000), FCM(1:50-100), IHC-P(1:50-200), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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