POU2F1 antibody (POU Domain, Class 2, Transcription Factor 1)

Details for Product anti-POU2F1 Antibody No. ABIN6944642
Target
Reactivity
Human, Mouse, Rat
103
35
26
4
4
3
3
3
3
3
2
1
Host
Rabbit
89
10
8
Clonality (Clone)
Monoclonal ()
Conjugate
This POU2F1 antibody is un-conjugated
7
5
5
5
5
5
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
93
54
38
13
7
5
4
3
2
1
1
1
Options
Immunogen Recombinant protein within human POU2F1 aa 1-150.
Clone 1C14
Isotype IgG
Purification Purified by Protein A.
Target
Alternative Name POU2F1 (POU2F1 Antibody Abstract)
Background

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

Subcellular location: Nucleus


Synonyms: POU domain class 2 transcription factor 1, NF-A1, Octamer-binding protein 1, Octamer-binding transcription factor 1, Oct-1, OTF-1, POU2F1, OCT1, OTF1
Gene ID 5451
UniProt P14859
Application Notes WB(1:500-2000), IHC-P(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months