Pro Caspase 9 (AA 250-350) antibody

Catalog No. ABIN6944661

This Rabbit Monoclonal antibody specifically detects Pro Caspase 9 in FACS and WB. It exhibits reactivity toward Human.

Quick Overview for Pro Caspase 9 (AA 250-350) antibody (ABIN6944661)

Target: Pro Caspase 9

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB)

Clone: 3T6

Product Details

Binding Specificity: AA 250-350

Purpose: pro Caspase 9 (3T6) Monoclonal Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Human Caspase-9 between 250 to 350 amino acids

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000), FCM(1:20-100)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details

Target: Pro Caspase 9

Background:

Synonyms: Caspase-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP-9, APAF-3, ICE-LAP6, CASP9

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Gene ID: 842

UniProt: P55211