STIP1 antibody (AA 1-150)

Catalog No. ABIN6945069

This Rabbit Monoclonal antibody specifically detects STIP1 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for STIP1 antibody (AA 1-150) (ABIN6945069)

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This STIP1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2H5

Product Details anti-STIP1 Antibody

Binding Specificity: AA 1-150

Purpose: STIP1 (2H5) Monoclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein orresponding to human STIP1 aa 1-150

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000), FCM(1:50-100), IHC-P(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for STIP1

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Alternative Name: STIP1

Background:

Synonyms: Stress-induced-phosphoprotein 1, Hsc70/Hsp90-organizing protein, Renal carcinoma antigen NY-REN-11, Transformation-sensitive protein IEF SSP 3521, STI1, Hop, STIP1

Background: Stress-induced-phosphoprotein 1 (STI1) functions as a co-chaperone for HSP70 and HSP90 during heat shock response. STI1 exists as either a monomer or a dimer, and this conformational flexibility facilitates its function in organizing HSP70/HSP90. HSP90 acts as an ATPase, and requires the recruitment of client proteins and proper conformation to function. STI1 acts as a "scaffold" for client protein recruitment to the relaxed, ADP-bound conformation of HSP90, thus suppressing ATP turnover during the loading phase and allowing proper function.

Gene ID: 10963

UniProt: P31948