WDR5 antibody

Catalog No. ABIN6945375

This Rabbit Polyclonal antibody specifically detects WDR5 in WB, IF and ChIP-seq. It exhibits reactivity toward Human.

Quick Overview for WDR5 antibody (ABIN6945375)

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ChIP DNA-Sequencing (ChIP-seq)

Product Details anti-WDR5 Antibody

Cross-Reactivity: Human

Purification: Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300

Immunogen: Polyclonal antibody raised in rabbit against human WDR5 (WD (tryptophan-aspartate) repeat domain 5), using a recombinant protein

Application Details

Application Notes: WB 1:300-5000
IF()
ChIP-seq()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 μg/μL

Buffer: PBS with 0.05 % sodium azide and 0.05 % Proclin300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for WDR5

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Alternative Name: WDR5

Background:

Synonyms: WD repeat-containing protein 5, WDR5, BMP2-induced 3-kb gene protein, BIG3

Background: Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

Gene ID: 11091

UniProt: P61964