CD79a antibody

Catalog No. ABIN6950817

This Mouse Monoclonal antibody specifically detects CD79a in IHC. It exhibits reactivity toward Human and Rat.

Quick Overview for CD79a antibody (ABIN6950817)

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD79a antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CD79a Antibody

Purpose: CD79a mouse mAb

Specificity: The antibody can specifically recognize human CD79a protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 100 - 226 of the human CD79a protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Alternative Name: CD79a

Background:

Synonyms: B lymphocyte-specific MB1 protein, B-cell antigen receptor complex-associated protein alpha chain, CD 79a, CD79a, CD79a antigen (immunoglobulin-associated alpha) , CD79A antigen, CD79a molecule, immunoglobulin-associated alpha, CD79A_HUMAN, Ig alpha, Ig-alpha, IGA, IgM-alpha, Immunoglobulin-associated alpha, Ly54, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein

Background: CD79a and CD79b form a heterodimer molecular complex. Together with the membrane surface immunoglobulin of B cells, they form the antigen recognition receptor of B cells, participate in the signal transduction of B cell activation, and can be a broad-spectrum marker of B cells. They can be labeled from the former B cells to mature plasma cells. Because the expression of CD79a decreased during terminal differentiation, the staining may be due to the cross reaction of CD79b. It is often used in combination with other antibodies for the diagnosis of B-cell lymphoma.

Gene Name: CD79A

Protein Name: CD79a

Gene ID: 973

UniProt: P11912

Pathways: BCR Signaling