HDAC6 antibody

Catalog No. ABIN6950860

The Mouse Monoclonal anti-HDAC6 antibody (ABIN6950860) specifically detects HDAC6 in IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for HDAC6 antibody (ABIN6950860)

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This HDAC6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-HDAC6 Antibody

Purpose: HDAC6 mouse mAb

Specificity: The antibody can specifically recognize human HDAC6 protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 1100 - 1215 of the human HDAC6 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Alternative Name: HDAC6

Background:

Synonyms: CPBHM, FLJ16239, HD 6, HD6, HDAC 6, HDAC6, HDAC6_HUMAN, Histone deacetylase 6 (HD6) , Histone deacetylase 6, JM 21, JM21, KIAA0901, OTTHUMP00000032398, OTTHUMP00000197663, PPP1R90, Protein phosphatase 1 regulatory subunit 90

Background: Histone deacetylase (HDAC) is a kind of protease, which plays an important role in chromosome structural modification and gene expression regulation. In general, histone acetylation is conducive to the dissociation of DNA and histone octamer and the relaxation of nucleosome structure, so that various transcription factors and synergistic transcription factors can specifically bind to DNA binding sites and activate gene transcription.

Gene Name: HDAC6

Protein Name: HDAC6

Gene ID: 10013

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling