THRA antibody (Atto 488)

Catalog No. ABIN6952045

The Atto 488-conjugated Mouse Monoclonal anti-THRA antibody (Clone H43) (ABIN6952045) specifically detects THRA in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for THRA antibody (Atto 488) (ABIN6952045)

Target: THRA (Thyroid Hormone Receptor, alpha (THRA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This THRA antibody is conjugated to Atto 488

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: H43

Product Details anti-THRA Antibody (Atto 488)

Specificity: Activated T lymphocytes,Detects 70 kDa.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein A Purified

Immunogen: Synthetic peptide from the full length Human Thyroid hormone receptor protein

Isotype: IgG2a

Application Details

Application Notes:

• WB (1:500)
• optimal dilutions for assays should be determined by the user.

Comment:

A 1:500 dilution of ABIN6952045 was sufficient for detection of Pan-Thyroid hormone receptor in 10 ug of Hep G2 Human Hepatoblastoma Cell lysate by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for THRA

Target: THRA (Thyroid Hormone Receptor, alpha (THRA))

Alternative Name: Thyroid Hormone Receptor

Background: Thryoid hormone receptors are ligand dependent members of the steroid/retinoic acid superfamily of transcription factors. Thyroid hormones affect metabolic processes, growth and development.

Gene ID: 7067

NCBI Accession: NM_001190918

UniProt: P10827

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development