CHD1 antibody (C-Term)

Catalog No. ABIN6952376

This Rabbit Polyclonal antibody specifically detects CHD1 in WB, IP, ChIP and ChIP-seq. It exhibits reactivity toward Human.

Quick Overview for CHD1 antibody (C-Term) (ABIN6952376)

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Grade: ChIP-seq Grade

Product Details anti-CHD1 Antibody

Binding Specificity: C-Term

Specificity: Polyclonal antibody raised in rabbit against human CHD1 (Chromodomain Helicase DNA Binding Protein 1), using a synthetic peptide containing a sequence from the C-terminal part of the protein.

Purification: Affinity purified

Immunogen: synthetic peptide

Application Details

Application Notes: ChIP 1 μg:ChIP
WB 1:2,000
IP 3 μg:IP

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 μg/μL

Buffer: TBS, 0,1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CHD1

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Alternative Name: CHD1

Background: CHD1 (UniProtKB/Swiss-Prot entry O14646) functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. It is required for the recognition of H3K4me3 by the FACT and PAF complexes as well as the U2 snRNP complex and regulates both polymerase II and polymerase I transcription. CHD1 further negatively regulates DNA replication and is required for maintaining open chromatin and pluripotency in embryonic stem cells.

UniProt: O14646

Pathways: Chromatin Binding