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CBX2 antibody (C-Term)

This anti-CBX2 antibody is a Rabbit Polyclonal antibody detecting CBX2 in WB, ChIP, IP and ChIP-seq. Suitable for Human.
Catalog No. ABIN6952393

Quick Overview for CBX2 antibody (C-Term) (ABIN6952393)

Target

See all CBX2 Antibodies
CBX2 (Chromobox Homolog 2 (CBX2))

Reactivity

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  • 27
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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This CBX2 antibody is un-conjugated

Application

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Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), ChIP DNA-Sequencing (ChIP-seq)
  • Binding Specificity

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    C-Term

    Specificity

    Polyclonal antibody raised in rabbit against human CBX2 (chromobox 2), using a synthetic peptide containing a sequence from the C-terminus of the protein

    Purification

    Affinity purified

    Immunogen

    synthetic peptide
  • Application Notes

    ChIP/ChIP-seq 1 μg:ChIP
    WB 1:1,000
    IP 6 μg:IP

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Tris-citrate/phosphate buffer, 0.05 % azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C
  • Target

    CBX2 (Chromobox Homolog 2 (CBX2))

    Alternative Name

    CBX2

    Background

    CBX2 (UniProtKB/Swiss-Prot entry Q14781) is a component of the PRC1-like polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. The PRC1 complex mediates monoubiquitination of histone H2A on lysine 119, introducing heritably changed expression. CBX2 is involved in sexual development. Mutations in CBX2 are associated with gonadal dysgenesis in humans.

    UniProt

    Q14781
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