CBX2 antibody (C-Term)

Catalog No. ABIN6952393

The Rabbit Polyclonal anti-CBX2 antibody (ABIN6952393) specifically detects CBX2 in WB, ChIP, IP and ChIP-seq. The antibody is reactive with Human samples.

Quick Overview for CBX2 antibody (C-Term) (ABIN6952393)

Target: CBX2 (Chromobox Homolog 2 (CBX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX2 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), ChIP DNA-Sequencing (ChIP-seq)

Product Details anti-CBX2 Antibody

Binding Specificity: C-Term

Specificity: Polyclonal antibody raised in rabbit against human CBX2 (chromobox 2), using a synthetic peptide containing a sequence from the C-terminus of the protein

Purification: Affinity purified

Immunogen: synthetic peptide

Application Details

Application Notes: ChIP/ChIP-seq 1 μg:ChIP
WB 1:1,000
IP 6 μg:IP

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Tris-citrate/phosphate buffer, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CBX2

Target: CBX2 (Chromobox Homolog 2 (CBX2))

Alternative Name: CBX2

Background: CBX2 (UniProtKB/Swiss-Prot entry Q14781) is a component of the PRC1-like polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. The PRC1 complex mediates monoubiquitination of histone H2A on lysine 119, introducing heritably changed expression. CBX2 is involved in sexual development. Mutations in CBX2 are associated with gonadal dysgenesis in humans.

UniProt: Q14781