CBX2 antibody (C-Term)
Quick Overview for CBX2 antibody (C-Term) (ABIN6952393)
Target
See all CBX2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- Polyclonal antibody raised in rabbit against human CBX2 (chromobox 2), using a synthetic peptide containing a sequence from the C-terminus of the protein
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Purification
- Affinity purified
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Immunogen
- synthetic peptide
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Application Notes
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ChIP/ChIP-seq 1 μg:ChIP
WB 1:1,000
IP 6 μg:IP -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Tris-citrate/phosphate buffer, 0.05 % azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- CBX2 (Chromobox Homolog 2 (CBX2))
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Alternative Name
- CBX2
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Background
- CBX2 (UniProtKB/Swiss-Prot entry Q14781) is a component of the PRC1-like polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. The PRC1 complex mediates monoubiquitination of histone H2A on lysine 119, introducing heritably changed expression. CBX2 is involved in sexual development. Mutations in CBX2 are associated with gonadal dysgenesis in humans.
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UniProt
- Q14781
Target
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