MLL1 antibody

Catalog No. ABIN6952424

This Rabbit Polyclonal antibody specifically detects MLL1 in ChIP, ELISA and ChIP-seq. It exhibits reactivity toward Human.

Quick Overview for MLL1 antibody (ABIN6952424)

Target: MLL1 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLL1 antibody is un-conjugated

Application: Chromatin Immunoprecipitation (ChIP), ELISA, ChIP DNA-Sequencing (ChIP-seq)

Grade: ChIP-seq Grade

Product Details anti-MLL1 Antibody

Specificity: Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.

Purification: whole antiserum

Immunogen: synthetic peptide

Application Details

Application Notes: ChIP/ChIP-seq 2 μL:ChIP
ELISA 1:100 - 1:1,000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: serum, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MLL1

Target: MLL1 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1))

Alternative Name: MLL1

Background: MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.

UniProt: Q03164