SARS-CoV-2 Spike S1 antibody

Catalog No. ABIN6953206

The Human Chimeric anti-SARS-CoV-2 Spike S1 antibody has been validated for ELISA and Neut. It is suitable to detect SARS-CoV-2 Spike S1 in samples from SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha, SARS CoV-2 Beta, SARS CoV-2 Epsilon and SARS CoV-2 Gamma.

Quick Overview for SARS-CoV-2 Spike S1 antibody (ABIN6953206)

Target: SARS-CoV-2 Spike S1

Reactivity: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha, SARS CoV-2 Beta, SARS CoV-2 Epsilon, SARS CoV-2 Gamma

Host: Human

Clonality: Chimeric

Conjugate: This SARS-CoV-2 Spike S1 antibody is un-conjugated

Application: ELISA, Neutralization (Neut)

Clone: AM122

Product Details anti-SARS-CoV-2 Spike S1 Antibody

Cross-Reactivity (Details): The cross-reactivity with other coronaviruses has not been tested yet.

Characteristics: Anti-SARS-CoV-2 Spike S1 Antibody, Chimeric MAb is a chimeric monoclonal antibody combining the constant domains of the human IgG1 Molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified recombinant SARS-CoV-2 Spike S1 Protein.

Sterility: 0.22 μm filtered

Isotype: IgG1

Application Details

Application Notes: It is recommended to use antibody (ABIN6953206) and (ABIN6953207) as a pair set to detect SARS-CoV-2 Spike S1 in ELISA or serological assays.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4 . Normally trehalose is added as protectant before lyophilization.

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: For long term storage, the product should be stored at lyophilized state at -20°C or lower.
This product is stable after storage at:
4-8°C for 12 months in lyophilized state,
-70°C for 3 years under sterile conditions after reconstitution.

Target Details for SARS-CoV-2 Spike S1

Target: SARS-CoV-2 Spike S1

Target Type: Viral Protein

Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.