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SARS-CoV-2 Spike S1 antibody

Reactivity: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha, SARS CoV-2 Epsilon, SARS CoV-2 Gamma, SARS CoV-2 Beta ELISA, Neut Host: Human Chimeric AM122 unconjugated
Catalog No. ABIN6953206
  • Target See all SARS-CoV-2 Spike S1 Antibodies
    SARS-CoV-2 Spike S1
    Reactivity
    • 44
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha, SARS CoV-2 Epsilon, SARS CoV-2 Gamma, SARS CoV-2 Beta
    Host
    • 18
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Clonality
    • 32
    • 9
    • 4
    Chimeric
    Conjugate
    • 39
    • 3
    • 1
    • 1
    • 1
    This SARS-CoV-2 Spike S1 antibody is un-conjugated
    Application
    • 44
    • 9
    • 9
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Neutralization (Neut)
    Cross-Reactivity (Details)
    The cross-reactivity with other coronaviruses has not been tested yet.
    Characteristics
    Anti-SARS-CoV-2 Spike S1 Antibody, Chimeric MAb is a chimeric monoclonal antibody combining the constant domains of the human IgG1 Molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified recombinant SARS-CoV-2 Spike S1 Protein.
    Sterility
    0.22 μm filtered
    Clone
    AM122
    Isotype
    IgG1
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  • Application Notes
    It is recommended to use antibody (ABIN6953206) and (ABIN6953207) as a pair set to detect SARS-CoV-2 Spike S1 in ELISA or serological assays.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4 . Normally trehalose is added as protectant before lyophilization.
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    For long term storage, the product should be stored at lyophilized state at -20°C or lower.
    This product is stable after storage at:
    4-8°C for 12 months in lyophilized state,
    -70°C for 3 years under sterile conditions after reconstitution.
  • Target
    SARS-CoV-2 Spike S1
    Abstract
    SARS-CoV-2 Spike S1 Products
    Synonyms
    E2 antibody, Surface Glycoprotein antibody, S antibody
    Target Type
    Viral Protein
    Background
    It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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