BTLA antibody (APC)

Catalog No. ABIN7278031

This anti-BTLA antibody is a Armenian Hamster Monoclonal antibody detecting BTLA in FACS. Suitable for Mouse.

Quick Overview for BTLA antibody (APC) (ABIN7278031)

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivity: Mouse

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: This BTLA antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: 6A6

Product Details anti-BTLA Antibody (APC)

Purification: This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

Isotype: IgG

Application Details

Application Notes: This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.

Comment:

0.2 mg/mL

Restrictions: For Research Use only

Handling

Buffer: 10  mM NaH2PO4, 150  mM NaCl, 0.09 %  Sodium azide, 0.1 % gelatin,  pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C protected from light

Expiry Date: 12 months

Target Details for BTLA

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Alternative Name: CD272

Background: The 6A6 antibody reacts with mouse CD272, a type 1 transmembrane glycoprotein and member of the Ig superfamily. CD272, also known as BTLA (B and T Lymphocyte Attenuator), is expressed on peripheral lymphocytes as well as developing B and T cells, macrophages, and dendritic cells. CD272 is a receptor for CD270 (HVEM) and is structurally similar to CD152 (CTLA-4) and CD279 (PD-1) and functions as a negative regulator of B and T cell responses.

Gene ID: 208154

UniProt: Q3U0X8

Pathways: Cancer Immune Checkpoints