BTLA antibody (APC)
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- Target See all BTLA Antibodies
- BTLA (B and T Lymphocyte Associated (BTLA))
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Reactivity
- Mouse
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Host
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Armenian Hamster
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Clonality
- Monoclonal
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Conjugate
- This BTLA antibody is conjugated to APC
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Application
- Flow Cytometry (FACS)
- Purification
- This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
- Clone
- 6A6
- Isotype
- IgG
- Top Product
- Discover our top product BTLA Primary Antibody
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- Application Notes
- This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.
- Comment
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0.2 mg/mL
- Restrictions
- For Research Use only
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- Buffer
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- 2-8°C protected from light
- Expiry Date
- 12 months
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- Target
- BTLA (B and T Lymphocyte Associated (BTLA))
- Alternative Name
- CD272 (BTLA Products)
- Synonyms
- BTLA antibody, BTLA1 antibody, CD272 antibody, A630002H24 antibody, B and T lymphocyte associated antibody, BTLA antibody, Btla antibody
- Background
- The 6A6 antibody reacts with mouse CD272, a type 1 transmembrane glycoprotein and member of the Ig superfamily. CD272, also known as BTLA (B and T Lymphocyte Attenuator), is expressed on peripheral lymphocytes as well as developing B and T cells, macrophages, and dendritic cells. CD272 is a receptor for CD270 (HVEM) and is structurally similar to CD152 (CTLA-4) and CD279 (PD-1) and functions as a negative regulator of B and T cell responses.
- Gene ID
- 208154
- UniProt
- Q3U0X8
- Pathways
- Cancer Immune Checkpoints
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