TIM3 antibody

Catalog No. ABIN6961763

This Rat Monoclonal antibody specifically detects TIM3 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for TIM3 antibody (ABIN6961763)

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TIM3 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: RMT3-23

Product Details anti-TIM3 Antibody

Purification: This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.

Isotype: IgG2a kappa

Application Details

Comment:

0.5 mg/mL

Restrictions: For Research Use only

Handling

Buffer: 10 mM NaH2PO4, 150  mM NaCl, 0.09 %  Sodium azide, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

Expiry Date: 12 months

Target Details for TIM3

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Alternative Name: CD366 (TIM-3)

Target Type: Virus

Background: The RMT3-23 antibody reacts with mouse CD366 which is also known as Tim-3 (T cell immunoglobulin and mucin domain containing protein-3). Tim-3 is expressed on activated monocytes, macrophages, dendritic cells, and mast cells. Additionally, Tim-3 is found on Th1 lymphocytes and functions as an inhibitory receptor involved in the maintenance of immune homeostasis and self tolerance.

Gene ID: 171285

UniProt: Q8VIM0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints