ICOSLG antibody

Catalog No. ABIN6961772

This Rat Monoclonal antibody specifically detects ICOSLG in FACS. It exhibits reactivity toward Mouse.

Quick Overview for ICOSLG antibody (ABIN6961772)

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ICOSLG antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: HK5-3

Product Details anti-ICOSLG Antibody

Purification: This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.

Isotype: IgG2a kappa

Application Details

Comment:

0.5 mg/mL

Restrictions: For Research Use only

Handling

Buffer: 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

Expiry Date: 12 months

Target Details for ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Alternative Name: CD275 (B7-H2)

Background: The HK5.3 antibody reacts with mouse CD275, an approximately 40 kDa protein that is a member of the Ig superfamily. CD275 is also known as B7-H2, ICOS ligand, and B7-RP1. CD275 is a ligand for ICOS (CD278) that is expressed on activated T cells. CD275 is expressed by antigen presenting cells including B cells, macrophages, and dendritic cells. The interaction of CD275 with its receptor ICOS plays an important role in T cell costimulation.

Gene ID: 50723

UniProt: Q9JHJ8

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation