IL-4 antibody

Catalog No. ABIN6963825

The Mouse Monoclonal anti-IL-4 antibody has been validated for ELISA and ELISpot. It is suitable to detect IL-4 in samples from Human and Non-Human Primate. There are 4+ publications available.

Quick Overview for IL-4 antibody (ABIN6963825)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-4 antibody is un-conjugated

Application: ELISA, ELISpot

Clone: IL4-I

Product Details anti-IL-4 Antibody

Specificity: Native and recombinant IL-4

Cross-Reactivity (Details): The monoclonal antibody cross-reacts with IL-4 from non-human primates.

Characteristics: This monoclonal antibody enables specific detection of human IL-4 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human IL-4

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

ABIN6963825 and ABIN7448278 is recommended as capture mAb in ELISpot, FluoroSpot, and ELISA in combination with detection mAb ABIN6963825 and ABIN7448278I .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-4 antibody (ABIN6963825)

Hovanessian, Soundaramourty, Benferhat, Le Grand, Dereuddre-Bosquet, Krust, Estaquier et al.: "Vaccination with the Conserved Caveolin-1 Binding Motif in Human Immunodeficiency Virus Type 1 Glycoprotein gp41 Delays the Onset of Viral Infection and Provides Partial Protection in Simian/Human ..." in: Journal of virology, Vol. 92, Issue 18, (2018) (PubMed).

Weiwei, Xuexing, Chong, Yongkun, Qi, Hualei, Gary, Ying, Haijun, Zengguo, Na, Hang, Tiecheng, Yuwei, Junjie, Songtao, Xianzhu: "Marburg virus-like particles produced in insect cells induce neutralizing antibodies in rhesus macaques." in: Journal of medical virology, Vol. 89, Issue 12, pp. 2069-2074, (2018) (PubMed).

Camarca, Gianfrani, Ariemma, Cimmino, Bruzzese, Scerbo, Picascia, DEsposito, Beguinot, Formisano, Valentino: "Human Peripheral Blood Mononuclear Cell Function and Dendritic Cell Differentiation Are Affected by Bisphenol-A Exposure." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161122, (2017) (PubMed).

Stuehler, Kuenzli, Jaeger, Baettig, Ferracin, Rajacic, Kaiser, Bernardini, Forrer, Weisser, Elzi, Battegay, Halter, Passweg, Khanna: "Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation and Association With Occurrence and Outcome of Invasive Aspergillosis." in: The Journal of infectious diseases, Vol. 212, Issue 6, pp. 959-67, (2015) (PubMed).

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL4

Gene ID: 3565

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation