Cited in 4+ publications.
The Rat Monoclonal anti-IL-12/IL-23 p40 antibody (Clone C15-6) (ABIN6963862) specifically detects IL-12/IL-23 p40 in ELISA and ELISpot.
The antibody is reactive with Mouse samples.
Quick Overview for IL-12/IL-23 p40 antibody (ABIN6963862)
Target
IL-12/IL-23 p40
Reactivity
Mouse
Host
Rat
Clonality
Monoclonal
Conjugate
This IL-12/IL-23 p40 antibody is un-conjugated
Application
ELISA, ELISpot
Clone
C15-6
Specificity
Native and recombinant p40 subunit of mouse IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).
Purification
Purified from in vitro cultures by protein G affinity chromatography.
Reactivity: Human
ICFC
Host: Mouse
Monoclonal
C8-6
PE
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
supplied at 1 mg/mL in PBS with 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
Expiry Date
18 months
Bain, Oliphant, Thomson, Kullberg, Mowat: "Proinflammatory Role of Monocyte-Derived CX3CR1int Macrophages in Helicobacter hepaticus-Induced Colitis." in: Infection and immunity, Vol. 86, Issue 2, (2018) (PubMed).
Quast, Keller, Weber, Schneider, von Gunten, Lünemann: "Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation." in: Journal of neuroinflammation, Vol. 13, pp. 42, (2016) (PubMed).
Rahman, Chuquimia, Petursdottir, Periolo, Singh, Fernández: "Impact of toll-like receptor 2 deficiency on immune responses to mycobacterial antigens." in: Infection and immunity, Vol. 79, Issue 11, pp. 4649-56, (2011) (PubMed).
Pavlenko, Leder, Moreno, Levitsky, Pisa: "Priming of CD8+ T-cell responses after DNA immunization is impaired in TLR9- and MyD88-deficient mice." in: Vaccine, Vol. 25, Issue 34, pp. 6341-7, (2007) (PubMed).