IL-12/IL-23 p40 antibody
Quick Overview for IL-12/IL-23 p40 antibody (ABIN6963862)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Native and recombinant p40 subunit of mouse IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).
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Purification
- Purified from in vitro cultures by protein G affinity chromatography.
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Sterility
- 0.2 μm filtered
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Immunogen
- Recombinant mouse IL-12 p70
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- supplied at 1 mg/mL in PBS with 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
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Expiry Date
- 18 months
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: "Proinflammatory Role of Monocyte-Derived CX3CR1int Macrophages in Helicobacter hepaticus-Induced Colitis." in: Infection and immunity, Vol. 86, Issue 2, (2018) (PubMed).
: "Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation." in: Journal of neuroinflammation, Vol. 13, pp. 42, (2016) (PubMed).
: "Impact of toll-like receptor 2 deficiency on immune responses to mycobacterial antigens." in: Infection and immunity, Vol. 79, Issue 11, pp. 4649-56, (2011) (PubMed).
: "Priming of CD8+ T-cell responses after DNA immunization is impaired in TLR9- and MyD88-deficient mice." in: Vaccine, Vol. 25, Issue 34, pp. 6341-7, (2007) (PubMed).
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: "Proinflammatory Role of Monocyte-Derived CX3CR1int Macrophages in Helicobacter hepaticus-Induced Colitis." in: Infection and immunity, Vol. 86, Issue 2, (2018) (PubMed).
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- IL-12/IL-23 p40
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Alternative Name
- IL12/23 (p40)
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Gene ID
- 16160
Target
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