IL-10 antibody

Catalog No. ABIN6964017

The Rat Monoclonal anti-IL-10 antibody has been validated for Neut. It is suitable to detect IL-10 in samples from Human. There are 4+ publications available.

Quick Overview for IL-10 antibody (ABIN6964017)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-10 antibody is un-conjugated

Application: Neutralization (Neut)

Clone: 9D7

Product Details anti-IL-10 Antibody

Specificity: Native and recombinant human IL-10

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human IL-10

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-10 antibody (ABIN6964017)

Li, Ma, Xu: "Follicular regulatory T cells infiltrated the ovarian carcinoma and resulted in CD8 T cell dysfunction dependent on IL-10 pathway." in: International immunopharmacology, Vol. 68, pp. 81-87, (2019) (PubMed).

Le, Tversky, Chichester, Bieneman, Huang, Wood, Schroeder: "Interferons modulate Fc epsilon RI-dependent production of autoregulatory IL-10 by circulating human monocytoid dendritic cells." in: The Journal of allergy and clinical immunology, Vol. 123, Issue 1, pp. 217-23, (2009) (PubMed).

Minang, Areström, Zuber, Jönsson, Troye-Blomberg, Ahlborg: "Nickel-induced IL-10 down-regulates Th1- but not Th2-type cytokine responses to the contact allergen nickel." in: Clinical and experimental immunology, Vol. 143, Issue 3, pp. 494-502, (2006) (PubMed).

Katsikis, Chu, Brennan, Maini, Feldmann: "Immunoregulatory role of interleukin 10 in rheumatoid arthritis." in: The Journal of experimental medicine, Vol. 179, Issue 5, pp. 1517-27, (1994) (PubMed).

Target Details for IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Alternative Name: IL10

Gene ID: 3586

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints