IL-2 antibody

Catalog No. ABIN6964019

This Rat Monoclonal antibody specifically detects IL-2 in Neut. It exhibits reactivity toward Human and Non-Human Primateand has been mentioned in 1 publication.

Quick Overview for IL-2 antibody (ABIN6964019)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reactivity: Human, Non-Human Primate

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-2 antibody is un-conjugated

Application: Neutralization (Neut)

Clone: 17H12

Product Details anti-IL-2 Antibody

Specificity: Native and recombinant IL-2

Cross-Reactivity (Details): The antibody cross-reacts with IL-2 from non-human primates. Cross-reactivity has been tested in ELISA and/or ELISpot.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IL-2

Isotype: IgG2a

Application Details

Application Notes: Neutralization of human IL-2 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-2 antibody (ABIN6964019)

Jailwala, Waukau, Glisic, Jana, Ehlenbach, Hessner, Alemzadeh, Matsuyama, Laud, Wang, Ghosh: "Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation." in: PLoS ONE, Vol. 4, Issue 8, pp. e6527, (2010) (PubMed).

Target Details for IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Alternative Name: IL2

Gene ID: 3558

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation