GM-CSF antibody

Catalog No. ABIN6964026

The Rat Monoclonal anti-GM-CSF antibody has been validated for Neut. It is suitable to detect GM-CSF in samples from Human and Non-Human Primate. There are 2+ publications available.

Quick Overview for GM-CSF antibody (ABIN6964026)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reactivity: Human, Non-Human Primate

Host: Rat

Clonality: Monoclonal

Conjugate: This GM-CSF antibody is un-conjugated

Application: Neutralization (Neut)

Clone: 23B6

Product Details anti-GM-CSF Antibody

Specificity: Native and recombinant GM-CSF

Cross-Reactivity (Details): The antibody cross-reacts with GM-CSF from non-human primates. Cross-reactivity has been tested in ELISA and/or ELISpot.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human GM-CSF

Isotype: IgG2a

Application Details

Application Notes: Neutralization of human GM-CSF bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-GM-CSF antibody (ABIN6964026)

Scian, Barrionuevo, Giambartolomei, Fossati, Baldi, Delpino: "Granulocyte-macrophage colony-stimulating factor- and tumor necrosis factor alpha-mediated matrix metalloproteinase production by human osteoblasts and monocytes after infection with Brucella abortus." in: Infection and immunity, Vol. 79, Issue 1, pp. 192-202, (2011) (PubMed).

Kelly, Koziol-White, Clay, Liu, Bates, Bertics, Jarjour: "Potential contribution of IL-7 to allergen-induced eosinophilic airway inflammation in asthma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1404-10, (2009) (PubMed).

Target Details for GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Alternative Name: GMCSF

Gene ID: 1437

Pathways: JAK-STAT Signaling, Cellular Response to Molecule of Bacterial Origin