ATAD2 antibody (C-Term)

Catalog No. ABIN6971405

This Rabbit Polyclonal antibody specifically detects ATAD2 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for ATAD2 antibody (C-Term) (ABIN6971405)

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATAD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-ATAD2 Antibody

Binding Specificity: C-Term

Characteristics: ATAD2 (ATPase family AAA domain-containing protein 2) may be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. ATAD2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of human ATAD2.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for ATAD2

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Alternative Name: ATAD2

Molecular Weight: 160 kDa

NCBI Accession: NP_054828