CBX8 antibody (C-Term)

Catalog No. ABIN6971507

This Rabbit Polyclonal antibody specifically detects CBX8 in WB. It exhibits reactivity toward Human.

Quick Overview for CBX8 antibody (C-Term) (ABIN6971507)

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CBX8 Antibody

Binding Specificity: C-Term

Characteristics: CBX8 (chromobox homolog 8, PC3, RC1) is a Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. CBX8 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This CBX8 antibody was raised against a peptide corresponding to the C-terminal region of human CBX8 (Chromobox protein homolog 8).

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for CBX8

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Alternative Name: CBX8

Molecular Weight: 45 kDa

NCBI Accession: NP_065700