GATA4 antibody (C-Term)

Catalog No. ABIN6971676

The Rabbit Polyclonal anti-GATA4 antibody has been validated for WB. It is suitable to detect GATA4 in samples from Human and Mouse.

Quick Overview for GATA4 antibody (C-Term) (ABIN6971676)

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GATA4 Antibody

Binding Specificity: C-Term

Characteristics: GATA-4 is a zinc finger protein and part of the GATA family of sequence specific DNA binding transcription factors that recognize a consensus DNA sequence containing GATA. GATA-4 is involved in the development of several mesodermal and endodermal structures. GATA-4 mutant mice exhibit severe heart malformations. Defects in GATA-4 are the cause of atrial septal defect type 2. ASD2 is a congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria. GATA-4 also plays a role in regulating gene expression in cardiac and smooth muscle cell types. GATA-4 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human and Mouse samples.

Purification: Affinity Purified

Immunogen: This GATA-4 antibody was raised against a peptide derived from the C-terminus of human GATA-4.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for GATA4

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Alternative Name: GATA-4

Molecular Weight: 55 kDa

NCBI Accession: NP_002043

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis