RYBP antibody (C-Term)

Catalog No. ABIN6972657

The Rabbit Polyclonal anti-RYBP antibody has been validated for WB. It is suitable to detect RYBP in samples from Human and Mouse.

Quick Overview for RYBP antibody (C-Term) (ABIN6972657)

Target: RYBP (RING1 and YY1 Binding Protein (RYBP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RYBP Antibody

Binding Specificity: C-Term

Characteristics: RYBP (RING1 and YY1 Binding Protein) is a member of a non-canonical PRC1 repressive complex composed of at least RING1B and ubiquitinated H2A. Also inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of transcription as a repressor of the transcriptional activity of E4TF1. RYBP antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human and Mouse samples.

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of human RYBP.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for RYBP

Target: RYBP (RING1 and YY1 Binding Protein (RYBP))

Alternative Name: RYBP

Molecular Weight: 35 kDa

NCBI Accession: NP_036366