SMYD3 antibody

Catalog No. ABIN6972764

Product Details anti-SMYD3 Antibody

Target: SMYD3 (SET and MYND Domain Containing 3 (SMYD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMYD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Smyd3 (SET and MYND domain containing 3) is a histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. Recently, Smyd3 was described as the methyltransferase responsible for a novel site of histone modification, H4K5 methylation. Smyd3 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunohistochemistry and Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within human Smyd3.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for SMYD3

Target: SMYD3 (SET and MYND Domain Containing 3 (SMYD3))

Alternative Name: Smyd3 (SMYD3 Products)

Synonyms: KMT3E antibody, ZMYND1 antibody, ZNFN3A1 antibody, bA74P14.1 antibody, 2410008A19Rik antibody, Zmynd1 antibody, SET and MYND domain containing 3 antibody, SMYD3 antibody, Smyd3 antibody

Molecular Weight: 50 kDa

NCBI Accession: NP_001161212