TRIM37 antibody (C-Term)

Catalog No. ABIN6972886

This anti-TRIM37 antibody is a Rabbit Polyclonal antibody detecting TRIM37 in WB. Suitable for Human and Mouse.

Quick Overview for TRIM37 antibody (C-Term) (ABIN6972886)

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM37 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM37 Antibody

Binding Specificity: C-Term

Characteristics: TRIM37 (Tripartite Motif Containing 37) is an E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:686, PubMed:972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:972). Mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:042). Has anti-HIV activity (PubMed:724). TRIM37 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human and Mouse samples.

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of human TRIM37.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for TRIM37

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Alternative Name: TRIM37

Molecular Weight: 120 kDa

NCBI Accession: NP_056109