TRIM37 antibody

Catalog No. ABIN7120286

Product Details anti-TRIM37 Antibody

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM37 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: tripartite motif-containing 37

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for TRIM37

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Alternative Name: TRIM37 (TRIM37 Products)

Synonyms: MUL antibody, POB1 antibody, TEF3 antibody, 1110032A10Rik antibody, 2810004E07Rik antibody, AI848587 antibody, AU043018 antibody, mKIAA0898 antibody, tripartite motif-containing 37 antibody, tripartite motif containing 37 antibody, Trim37 antibody, TRIM37 antibody

Background: Synonyms:TRIM37, POB1, TEF3, MUL, tripartite motif containing 37 Background:E3 ubiquitin-protein ligase required to prevent centriole reduplication(PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication(PubMed:23769972). Mediates monoubiquitination of 'Lys-119' of histone H2A(H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group(PcG) multiprotein PRC2-like complex and mediates repression of target genes(PubMed:25470042). Has anti-HIV activity(PubMed:24317724).

Molecular Weight: 100kDa, 130kDa

Gene ID: 4591

UniProt: O94972