AP3B1 antibody (AA 1-100) (AbBy Fluor® 555)

Catalog No. ABIN6978397

This Rabbit Polyclonal antibody specifically detects AP3B1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human, Mouse and Xenopus laevis.

Quick Overview for AP3B1 antibody (AA 1-100) (AbBy Fluor® 555) (ABIN6978397)

Target: AP3B1 (Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1))

Reactivity: Human, Mouse, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3B1 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-AP3B1 Antibody (AbBy Fluor® 555)

Binding Specificity: AA 1-100

Cross-Reactivity: Human, Mouse, Xenopus laevis

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Cat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HPS2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AP3B1

Target: AP3B1 (Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1))

Alternative Name: HPS2

Background:

Synonyms: AP-3 complex subunit beta-1, AP3B1, Adaptor protein complex AP-3 subunit beta-1, Adaptor-related protein complex 3 subunit beta-1, Beta-3A-adaptin, Clathrin assembly protein complex 3 beta-1 large chain, AP3B1, ADTB3A

Background: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles.

Gene ID: 8546

UniProt: O00203

Pathways: SARS-CoV-2 Protein Interactome