IL1A antibody (AA 21-113) (AbBy Fluor® 647)

Catalog No. ABIN6979775

The Rabbit Polyclonal anti-IL1A antibody has been validated for WB and FACS. It is suitable to detect IL1A in samples from Human, Mouse and Rat.

Quick Overview for IL1A antibody (AA 21-113) (AbBy Fluor® 647) (ABIN6979775)

Target: IL1A (Interleukin 1 alpha (IL1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1A antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-IL1A Antibody (AbBy Fluor® 647)

Binding Specificity: AA 21-113

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-1 Alpha Propeptide

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IL1A

Target: IL1A (Interleukin 1 alpha (IL1A))

Alternative Name: IL-1 Alpha Propeptide

Background:

Synonyms: interleukin-1 alpha, Hematopoietin 1, IL 1 alpha, IL1 alpha, IL 1, IL 1A, Il-1a, IL1, IL1A, IL1F1, ilia, Interleukin 1 alpha, Interleukin 1 alpha precursor, Interleukin1 alpha, Preinterleukin 1 alpha, Pro interleukin 1 alpha, Prointerleukin 1 alpha,

Background: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Gene ID: 3552

UniProt: P01583

Pathways: NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints