DNMT3A antibody (AA 51-150) (AbBy Fluor® 647)

Catalog No. ABIN6980432

The Rabbit Polyclonal anti-DNMT3A antibody has been validated for WB, FACS, IF (cc) and IF (p). It is suitable to detect DNMT3A in samples from Human, Mouse and Rat.

Quick Overview for DNMT3A antibody (AA 51-150) (AbBy Fluor® 647) (ABIN6980432)

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNMT3A antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DNMT3A Antibody (AbBy Fluor® 647)

Binding Specificity: AA 51-150

Cross-Reactivity: Human

Predicted Reactivity: Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNMT-3 alpha

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DNMT3A

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Alternative Name: DNMT-3 alpha

Background:

Synonyms: DNA (cytosine 5 ) methyltransferase 3 alpha, DNA (cytosine 5) methyltransferase 3A, DNA cytosine methyltransferase 3A2, DNA methyltransferase 3a, DNA methyltransferase HsaIIIA, DNA MTase HsaI, DNA MTase HsaIIIA, DNMT 3a, DNMT, Dnmt3a, DNMT3A2, M HsaIIIA, M.HsaIIIA, MCMT, Methyl CpG binding domain protein 3a.

Background: The tumor organization has the DNA methylation disorder, including and damps cancer gene high methylation DNA with the cell multiplication cycle close related cancer gene low methylation the methyl transferase (Dnmt) participation methylation the formation (is mainly Dnmt3a and Dnmt3b) and the maintenance (is mainly Dnmt1) (isoform CRA_b) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA)

Gene ID: 1788

UniProt: Q9Y6K1