DNMT3A antibody (2meLys44)

Catalog No. ABIN7258842

The Rabbit Polyclonal anti-DNMT3A antibody (ABIN7258842) specifically detects DNMT3A in IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DNMT3A antibody (2meLys44) (ABIN7258842)

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNMT3A antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-DNMT3A Antibody

Binding Specificity: 2meLys44

Characteristics: Methylated antibody

Purification: Affinity purification

Immunogen: A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_031898.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DNMT3A

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Alternative Name: DNMT3A

Background: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

Gene ID: 13435

UniProt: O88508