beta Catenin antibody (AA 501-600) (AbBy Fluor® 680)

Catalog No. ABIN6981223

This Rabbit Polyclonal antibody specifically detects beta Catenin in FACS, IF (cc) and IF (p). It exhibits reactivity toward Human and Rat.

Quick Overview for beta Catenin antibody (AA 501-600) (AbBy Fluor® 680) (ABIN6981223)

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Catenin antibody is conjugated to AbBy Fluor® 680

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-beta Catenin Antibody (AbBy Fluor® 680)

Binding Specificity: AA 501-600

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Beta catenin

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for beta Catenin

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Alternative Name: Beta catenin

Background:

Synonyms: beta-catenin, beta catenin, CTNNB1, CHBCAT, CTNNB1, CTNNB, PRO2286, Cadherin associated protein, Catenin (cadherin associated protein), beta 1, 88 kDa, Catenin beta 1, Catenin beta-1, CATNB, CTNB1_HUMAN, CTNNB, CTNNB1, DKFZp686D02253, FLJ25606, FLJ37923, b-catenin, OTTHUMP00000162082, OTTHUMP00000165222, OTTHUMP00000165223, OTTHUMP00000209288, OTTHUMP00000209289, Catenin-_, Catenin _.

Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009].

Gene ID: 1499

UniProt: P35222

Pathways: Peptide Hormone Metabolism