CENPC1 antibody (AbBy Fluor® 750)

Catalog No. ABIN6982541

The Rabbit Monoclonal anti-CENPC1 antibody has been validated for IF (cc) and FACS. It is suitable to detect CENPC1 in samples from Human, Mouse and Rat.

Quick Overview for CENPC1 antibody (AbBy Fluor® 750) (ABIN6982541)

Target: CENPC1 (Centromere Protein C 1 (CENPC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CENPC1 antibody is conjugated to AbBy Fluor® 750

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

Clone: 3A7

Product Details anti-CENPC1 Antibody (AbBy Fluor® 750)

Purification: Purified by Protein A.

Immunogen: Recombinant human CENPC1 protein

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for CENPC1

Target: CENPC1 (Centromere Protein C 1 (CENPC1))

Alternative Name: CENPC1

Background:

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

Subcellular location: Nucleus

Synonyms: CENP-C 1, CENP-C, CENPC_HUMAN, CENPC1, Centromere autoantigen C, Centromere autoantigen C1, Centromere protein C 1, ICEN7, Interphase centromere complex protein 7, MIF2.

Gene ID: 1060

UniProt: Q03188