SBNO1 antibody (AA 331-430) (Biotin)

Catalog No. ABIN6982639

This Rabbit Polyclonal antibody specifically detects SBNO1 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for SBNO1 antibody (AA 331-430) (Biotin) (ABIN6982639)

Target: SBNO1 (Strawberry Notch Homolog 1 (SBNO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SBNO1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SBNO1 Antibody (Biotin)

Binding Specificity: AA 331-430

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SBNO1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SBNO1

Target: SBNO1 (Strawberry Notch Homolog 1 (SBNO1))

Alternative Name: SBNO1

Background:

Synonyms: FLJ10701, FLJ10833, FLJ16176, Monocyte protein 3, MOP 3, MOP-3, MOP3, Protein strawberry notch homolog 1, SBNO 1, Sbno1, SBNO1_HUMAN, Sno, Sno strawberry notch homolog 1, Strawberry notch homolog 1.

Background: SBNO1 is a 1,392 amino acid protein encoded by the human gene of the same name located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism. It is most severe in cases of complete trisomy.

Gene ID: 55206

UniProt: A3KN83

Pathways: SARS-CoV-2 Protein Interactome