MAGMAS antibody (AA 31-125) (Biotin)

Catalog No. ABIN6982784

The Rabbit Polyclonal anti-MAGMAS antibody is suitable to detect MAGMAS in samples from Human. It has been validated for WB, IHC (p) and IHC (fro).

Quick Overview for MAGMAS antibody (AA 31-125) (Biotin) (ABIN6982784)

Target: MAGMAS (PAM16) (Presequence Translocase-Associated Motor 16 Homolog (PAM16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGMAS antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MAGMAS Antibody (Biotin)

Binding Specificity: AA 31-125

Purpose: PAM16 Polyclonal Antibody, Biotin Conjugated

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAM16

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MAGMAS

Target: MAGMAS (PAM16) (Presequence Translocase-Associated Motor 16 Homolog (PAM16))

Alternative Name: PAM16

Background:

Synonyms: CGI-136, MAGMAS, Magmas like protein, Mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction, Mitochondria-associated granulocyte macrophage CSF-signaling molecule, Mitochondrial import inner membrane translocase subunit TIM16, PAM16, Presequence translocase-associated motor 16 homolog (S. cerevisiae), Presequence translocated-associated motor subunit PAM16, TIM16, TIM16_HUMAN, TIMM16.

Background: This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities. [provided by RefSeq, May 2017]

Gene ID: 51025

UniProt: Q9Y3D7