IRS4 antibody (AA 551-650) (Biotin)

Catalog No. ABIN6982970

The Rabbit Polyclonal anti-IRS4 antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect IRS4 in samples from Human and Mouse.

Quick Overview for IRS4 antibody (AA 551-650) (Biotin) (ABIN6982970)

Target: IRS4 (Insulin Receptor Substrate 4 (IRS4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS4 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IRS4 Antibody (Biotin)

Binding Specificity: AA 551-650

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IRS-4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for IRS4

Target: IRS4 (Insulin Receptor Substrate 4 (IRS4))

Alternative Name: IRS-4

Background:

Synonyms: IRS4, 160 kDa phosphotyrosine protein, Insulin receptor substrate 4, IRS 4, PY160, IRS4_HUMAN, IRS-4, Phosphoprotein of 160 kDa, pp160.

Background: IRS4 (Insulin receptor substrate 4) is a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signaling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.

Gene ID: 8471

UniProt: O14654