IRS4 antibody (AA 551-650)

Catalog No. ABIN6989553

Product Details anti-IRS4 Antibody

Target: IRS4 (Insulin Receptor Substrate 4 (IRS4))

Binding Specificity: AA 551-650

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IRS-4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IRS4

Target: IRS4 (Insulin Receptor Substrate 4 (IRS4))

Alternative Name: IRS-4 (IRS4 Products)

Synonyms: IRS4 antibody, irs-4 antibody, py160 antibody, IRS-4 antibody, PY160 antibody, irs2 antibody, irs2-a antibody, insulin receptor substrate 4 antibody, insulin receptor substrate 4 S homeolog antibody, IRS4 antibody, irs4 antibody, Irs4 antibody, irs4.S antibody

Background:

Synonyms: IRS4, 160 kDa phosphotyrosine protein, Insulin receptor substrate 4, IRS 4, PY160, IRS4_HUMAN, IRS-4, Phosphoprotein of 160 kDa, pp160.

Background: IRS4 (Insulin receptor substrate 4) is a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signaling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.

Gene ID: 8471

UniProt: O14654