CR1L antibody (AA 51-150) (Cy5)

Catalog No. ABIN6984175

This Rabbit Polyclonal antibody specifically detects CR1L in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for CR1L antibody (AA 51-150) (Cy5) (ABIN6984175)

Target: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CR1L antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CR1L Antibody (Cy5)

Binding Specificity: AA 51-150

Cross-Reactivity: Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Crry

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CR1L

Target: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Alternative Name: Crry

Background:

Synonyms: Mcp, Crry, mCRY, Complement component receptor 1-like protein, Complement regulatory protein Crry, Protein p65, Cr1l, Cry

Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.

Gene ID: 12946

UniProt: Q64735

Pathways: Complement System