HSPBP1 antibody (AA 51-150) (Cy5)

Catalog No. ABIN6984382

This Rabbit Polyclonal antibody specifically detects HSPBP1 in IF (cc) and IF (p). It exhibits reactivity toward Rat.

Quick Overview for HSPBP1 antibody (AA 51-150) (Cy5) (ABIN6984382)

Target: HSPBP1 (HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPBP1 antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HSPBP1 Antibody (Cy5)

Binding Specificity: AA 51-150

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HspBP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HSPBP1

Target: HSPBP1 (HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))

Alternative Name: HspBP1

Background:

Synonyms: 1500019G21Rik, FES1, Heat shock protein 70 binding protein, Heat shock protein 70 interacting protein, Heat shock protein binding protein 1, Heat shock protein-binding protein 1, Heat-shock 70-KD protein-binding protein 1, HPBP1_HUMAN, Hsp 70 binding protein, Hsp 70 interacting protein, Hsp70 binding protein 1, Hsp70 binding protein 2, Hsp70 interacting protein 1, Hsp70 interacting protein 2, Hsp70-binding protein 1, Hsp70-binding protein 2, Hsp70-interacting protein 1, Hsp70-interacting protein 2, HSPA (heat shock 70 kDa) binding protein, cytoplasmic cochaperone 1, HSPA-binding protein 1, HSPBP, HspBP1, HspBP2, PP1845.

Background: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.

Gene ID: 23640

UniProt: Q9NZL4